Si trova su / Altri legami
© 2021 American Chemical Society and American Society of Pharmacognosy.Four new aromatic polyketides, wailupemycins M–P (1–4), and two new hydroxamate siderophores, streptamides A (5) and B (6), together with the previously reported nocardamine (7), were isolated from the marine–algae–derived Streptomyces sp. OUCMDZ–3434. Wailupemycins M–P (1–4), possessing an α–pyrone moiety, were isolated from the extract of a liquid fermentation, and the siderophores (5–7) were isolated from the extract of a solid fermentation. Their structures were assigned based on detailed spectroscopic analysis and quantum chemical calculations. Compounds 5–7 were capable of binding Fe(III). Compound 5 can form a tighter Fe(III) complex than that of deferoxamine B mesylate (DFB).
