Longipetalol A: A Highly Modified Triterpenoid from Dichapetalum longipetalum / Dong–Li Zhang; Min Li; Gui–Fang Han; Shao–Yong Li; De–Jun Jin; Sheng–An Tang
Si trova su / Altri legami
© 2021 American Chemical Society and American Society of Pharmacognosy.Longipetalol A (1) is an unprecedented highly modified triterpenoid with a unique 1,2–seco–3–(2–oxo–phenylethyl)–17α–13,30–cyclodammarane skeleton, featuring an acetal–lactone fragment. It was isolated from Dichapetalum longipetalum along with two additional derivatives, namely, longipetalols B (2) and C (3). Their structures were elucidated using spectroscopic analyses combined with single–crystal X–ray diffraction. Compounds 1, 2, and 3 exhibited inhibitory effects on nitric oxide production in lipopolysaccharide–induced RAW264.7 macrophages.
